| 
								         	ER Carey et al    												Addictive Behaviors Reports 8(2018)95 101
<br />     	confirmed curiosity,intention to use,and peer influence are significant     independent of susceptibility (Pierce et al., 2005), warranting further
<br />     	and appropriate items to consider in measuring susceptibility to e-ci-     examination of factors leading Hispanic adolescents to be more curious
<br />     	garettes, cigarettes,hookah, and cigars among this adolescent popula-     about these products. Despite a higher reported prevalence of sus-
<br />     	tion.Across products,we observed minor differences in the strength of     ceptibility to e-cigarettes and cigarettes among Hispanic adolescents,no
<br />     	each item.Specifically,curiosity had the weakest relationship with the     significant interactions were observed between ethnicity and suscept-
<br />     	underlying susceptibility construct across all products, peer influence     ibility in predicting future use.Although more Hispanic adolescents are
<br />     	had the strongest relationship with susceptibility to e-cigarettes, ci-     susceptible to e-cigarettes and cigarettes than their non-Hispanic peers
<br />     	garettes, and hookah, and future intentions had the strongest re-     (and Hispanic adolescents endorse curiosity about products more than
<br />     	lationship with susceptibility to cigars.While all three factors may be     non-Hispanic peers), the relationship between the measure of suscept-
<br />     	influential in determining adolescent susceptibility to tobacco products,     ibility itself and ever use of e-cigarettes and cigarettes is consistent
<br />     	intervention efforts to alter susceptibility may need to be tailored by     across ethnic groups.This suggests that tailoring interventions designed
<br />     	product.    								to ameliorate susceptibility among Hispanics to address curiosity might
<br />		We observed almost 30% of adolescents were susceptible to a-ci-     be particularly useful.
<br />     	garettes at baseline,a prevalence nearly double that of each individual
<br />     	combustible product.Adolescents may be more susceptible to e-cigar-     4.1. Strengths and limitations
<br />     	ettes than other products, and more research is needed to investigate
<br />     	factors driving increased susceptibility, like the appeal of flavors	One study limitation is the low prevalence of ever users at future
<br />     	(Ambrose et al., 2015) or increased television and digital media mar-     time points for specific products,like hookah and cigars.This prevented
<br />     	keting(Duke et al.,2014;Mantey,Cooper,Clendennen,Pasch,&Perry,     examination of susceptibility to these products separately at baseline
<br />     	2016;Pierce et al.,2017).As expected,we observed susceptibility to e-     regarding future use; thus, we cannot draw conclusions about specific
<br />     	cigarettes and combustible products predicts product use at time points     predictive validity of susceptibility to individual combustible products.
<br />     	6, 12, and 18 months in the future. This is consistent with previous     Still, our examination of combustible products as a whole provides
<br />     	research(Bold et al.,2017;Cole et al.,2017;Jackson,1998;Jackson&     evidence for susceptibility as a predictor of product use among ado-
<br />     	Dickinson, 2004; Nodora et al., 2014; Pierce et al., 1996, 2005;     lescents. Additionally, our three-item construct only includes a single
<br />     	Spelman et al.,2009;Strong et al.,2015;Unger et al., 1997)and sug-     measure of intentions to use tobacco in the future, rather than both
<br />     	gests targeting and lessening susceptibility through intervention efforts     measures originally considered by Pierce et al.(2005),which may limit
<br />     	remains a significant factor in preventing initiation of multiple forms of     the ability to make comparisons between our susceptibility measures
<br />     	product use among adolescents.    					and those used in other studies.Next,this study population is limited by
<br />		Of note, the declining magnitude of the odds ratios predicting in-     geography,so findings may not be generalizable to adolescents outside
<br />     	itiation from any combustible product over time was not statistically     Texas. Finally, despite utilizing measures adapted from established
<br />     	different from each other, based on a comparison of their 95% con-     surveys(Hyland et al.,2017)and thorough cognitive testing,self-report
<br />     	fidence intervals.In contrast,the declining odds ratios for susceptibility     of data may lead to response bias.
<br />     	to e-cigarette use over time show a significant drop in influence on ever	Despite limitations, this study is strengthened by the large,diverse
<br />     	use at 18 months from susceptibility assessed at baseline.This suggests     population of Texas adolescents, which provided adequate power to
<br />     	that by 18 months when compared to 6 and 12 months, other factors     examine specific associations across ethnic groups and products. The
<br />     	exert a stronger influence on experimentation relative to susceptibility     complex survey design and use of analyses accounting for sampling
<br />     	status assessed 18 months earlier. In turn, this suggests that assessing     weights and clustering within schools yield results representative of the
<br />     	susceptibility to e-cigarettes more frequently may be necessary to in-     overall population of urban Texas adolescents in grades 6, 8, and 10.
<br />     	form the development of targeted long-term interventions, as is iden-     This study's longitudinal design and breadth of tobacco products allows
<br />     	tification of other factors that may be proximally related to e-cigarette     for investigation of all products concurrently, within the same popu-
<br />     	use.									lation and across time points, permitting temporal conclusions about
<br />		Congruous with our second hypothesis,we found the measurement     the role of susceptibility on future initiation, and extending past re-
<br />     	of each susceptibility construct across products applied equally well     search,which has yet to examine multiple product types longitudinally
<br />     	across ethnic groups. Results among groups were consistent with the     among the same cohort.
<br />     	entire population,with minor differences.Among Hispanic adolescents,
<br />     	intention to use had the strongest relationship with susceptibility to     4.2. Conclusions
<br />     	cigarettes, while peer influence had the strongest relationship among
<br />     	non-Hispanic adolescents.In contrast,peer influence had the strongest	Susceptibility is a key construct for predicting future initiation of
<br />     	relationship with susceptibility to cigars among Hispanic adolescents,     tobacco;past research has examined its validity relevant to cigarettes,
<br />     	while intention to use had the strongest relationship among non-     but not among contemporary adolescent populations and the changing
<br />     	Hispanic adolescents. Additionally, ethnicity was significant to the     landscape of tobacco products.This study confirms the appropriateness
<br />     	measurement of susceptibility to e-cigarettes as a whole;the differences     of the measurement of susceptibility (Pierce et al., 2005) across four
<br />     	in the model when considering ethnicity suggest that while the mea-     products(e-cigarettes,hookah,cigars,and cigarettes)and ethnic groups
<br />     	surement of susceptibility to e-cigarettes is valid across ethnic groups,     (Hispanic versus non-Hispanic), and the utility of susceptibility in
<br />     	the meaning of the construct may vary slightly depending on ethnicity.     predicting future tobacco product use among adolescents.Implications
<br />     	Thus,while it is appropriate to utilize the same susceptibility measure     for intervention and research emphasize the importance of suscept-
<br />     	across ethnic groups, specific influences may be more relevant to pre-     ibility in predicting initiation of product use and the need to investigate
<br />     	dicting susceptibility for Hispanics vs. non-Hispanics depending on     factors influencing susceptibility to specific products,like e-cigarettes,
<br />     	product type, and specifically, susceptibility to e-cigarettes should be     especially among Hispanic adolescents.
<br />     	considered separately by ethnicity.
<br />		While we expected Hispanic adolescents would have a higher pre-     Compliance with ethical standards
<br />     	valence of susceptibility to each product than non-Hispanic adolescents,
<br />     	this was observed only for e-cigarettes and cigarettes, with curiosity     Ethical approval
<br />     	about these products endorsed more often among Hispanic adolescents.
<br />     	This is consistent with previous research (Margolis et al., 2016), and	TATAMS was approved by the University of Texas Health Science
<br />     	notable, as curiosity predicts future experimentation with smoking     Center at Houston Institutional Review Board (HSC-SPH-13-0377).All
<br />      										100
<br />
								 |