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To quantify noncarcinogenic impacts, the hazard index approach was used. The hazard index <br />assumes that subthreshold exposures adversely affect a specific organ or organ system (i.e., <br />toxicological endpoint). For each discrete pollutant exposure, target organs presented in <br />regulatory guidance were utilized. <br />To calculate the hazard index, the pollutant concentration or dose is divided by the appropriate <br />toxicity value. For compounds affecting the same toxicological endpoint, this ratio is summed. <br />Where the total equals or exceeds one (i.e., unity), a health hazard is presumed to exist. For <br />chronic exposures, REL's were converted to units expressed in mg/kg/day to accommodate the <br />above referenced intake algorithm. To assess acute noncancer impacts, the maximum pollutant <br />concentration is divided by the REL for the corresponding averaging time (e.g., 1-hour). No <br />exposure adjustments are considered for short duration exposures. <br />Appendix 3.2, summarizes the REL's and corresponding reference dose values used in the <br />evaluation of chronic noncarcinogenic and acute exposures. The noncancer hazard quotient for <br />identified compounds generated from each source and a summation for each toxicological <br />endpoint are presented on this table. <br />For chronic noncarcinogenic effects, the hazard index identified for each toxicological endpoint <br />totaled less than the threshold of 1.0 for all exposure scenarios. For acute exposures, the hazard <br />indices for the identified averaging times did not exceed the threshold of 1.0. Therefore, acute <br />and chronic non -carcinogenic hazards were predicted to be within acceptable limits and are less <br />than significant. <br />5.3 POTENTIAL CANCER AND NON -CANCER RISKS2 <br />For carcinogenic exposures resulting from exposure to toxics from the freeway, the summation <br />of risk for the maximum exposed residential receptor totaled 3.58 in one million and will not <br />exceed the SCAQMD significance threshold of 10 in one million. <br />2 SCAQMD guidance does not require assessment of the potential health risk to on -site workers. Excerpts from the document OEHHA Air Toxics <br />Hot Spots Program Risk Assessment Guidelines —The Air Toxics Hot Spots Program Guidance Manual for Preparation of Health Risk <br />Assessments (OEHHA 2003), also indicate that it is not necessary to examine the health effects to on -site workers unless required by RCRA <br />(Resource Conservation and Recovery Act) / CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) orthe worker <br />resides on -site. <br />