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City of Santa Ana Emergency Operations Plan <br />Part I Basic Plan <br />2.4.10 Disease Outbreak/Pandemic <br />Disease Outbreak Definitions <br />A widespread disease outbreak with significant morbidity and mortality is one of the primary public health <br />concerns of the 21st century. Vaccines, antibiotics and improved living conditions resulted in dramatic declines <br />in communicable diseases in the latter part of the 20th century, and while transmission of communicable diseases <br />still occurs on a daily basis in every community, most instances are not of the severity or magnitude to be <br />considered an emergency. However, infectious diseases remain a threat to all persons in the City due to a variety <br />of factors, including: <br />• Population growth (denser populations, aging, migration), <br />• Methods of food production (widespread importation and distribution), <br />• Environmental changes (climate change, encroachment of humans on wild areas), <br />• Microbial adaptation (resistance to antibiotics, genetic mutations), <br />• Changes in health care (drugs causing immunosuppression, overuse of antibiotics), and <br />• Human behavior (travel, diet, compromised immune systems, failure to receive immunizations). <br />An outbreak, epidemic or pandemic, or the introduction of a novel disease, could pose a large threat to the health <br />of the community. A disease outbreak arises when the incidence of disease within a specific community or <br />geographical area during a specified time period (e.g. flu season) exceeds what would normally be expected. An <br />outbreak may occur with: <br />• A single case of a disease long absent from a population (e.g. smallpox), <br />• A disease organism, bacterium or virus not previously recognized in the community or geographical area, <br />• A previously endemic disease for which immunity has decreased due to lack of recent circulation and/or <br />decreased immunization rates, or <br />• The emergence of a previously unknown disease within a community. <br />An epidemic occurs when a disease outbreak becomes widely established in the community or geographical area, <br />and a pandemic occurs when the disease becomes prevalent in multiple regions, nations or continents. Outbreaks <br />may occur naturally or can be introduced intentionally through bioterrorism. Outbreaks may last for a few days, <br />weeks, or for several years. <br />Disease Outbreak Threats <br />According to the Orange County Health Care Agency (OCHCA), the diseases currently of concern for outbreak <br />in Orange County include: <br />• Influenza, including seasonal, novel and/or pandemic influenza strains, <br />• Childhood vaccine -preventable diseases such as measles and pertussis, <br />• Foodborne illness, including norovirus, salmonella or E. Coli, <br />• Vector -borne viruses such as West Nile Virus (WNV) or Zika, and <br />• Novel, emerging pathogens, such as Middle East Respiratory Syndrome, Coronavirus or Ebola. <br />Influenza, including Seasonal, Novel, and/or Pandemic Influenza Strains <br />Influenza is a contagious respiratory illness caused by a variety of influenza viruses. Although most flu illnesses <br />are mild and are similar to the common cold, severe cases cause on average more than 200,000 hospitalizations <br />and up to 49,000 deaths each year in the United States, primarily among older persons or persons with chronic <br />health conditions. In Orange County, severe influenza cases (defined as persons who have influenza and are <br />admitted to the intensive care unit or die) in persons less than 65 years of age are reportable. Orange County has <br />reported as many as 57 severe influenza cases, with 21 deaths, in one season during the annual outbreak period. <br />m <br />