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The Village Santa Ana Specific Plan Project <br />Dr. Lauren Salminen <br />Her work is part of the national Adolescent Brain Cognitive Development Study, the largest <br />investigation of its kind in the U.S. `We're adding the environmental factor, one of the least - <br />investigated areas," she says. <br />To understand the bigger picture across the Iifespan, Chen and Herting collaborated wit <br />Salminen, instructor of research neurology at the USC Mark and Mary Stevens Neuroimaging <br />and Informatics Institute, to create the ENIGMA -ENV Working Group. "We know things like <br />air pollution can increase dementia risk and vascular problems decades after exposure," <br />Salminen says. "But we have so much to learn about the processes that underlie those <br />cha n ges." <br />Together, they are pooling brain scans from more than 60,000 people worldwide, who span <br />all ages and range from healthy to those diagnosed with neurological disorders. Scientists <br />rely on geespatial technology to map each participant's home localtion and pollution <br />exposu re. <br />This global study builds on the success of ENIGMA Consortium, an international medical <br />network of neuroimaging researchers studying major diseases of the brain, led by USC <br />Stevens Associate Director Paul M- Thompson. 'The ENIGMA -ENV Working Group is a truly <br />global quest to identify environ menta I factors that help or harm our brain," says Thompson, <br />one of USC3s leading Alzheimer 3s researchers. 'Comparing data worldwide should reveal <br />what factors help our brains develop and age, and what protects us against mental illness, <br />which may ultimately guide public health policy." <br />The UEFA and its Triad Approach <br />The EPA pioneered a method of modeling the concentration of pollution at hazardous <br />wastes sites that also used geospatial technology. This method enabled the use of <br />Bayesian Analysis to view probability distributions of contaminants that would seem <br />to be Much more useful and precise than those used in your report. <br />IQ Air and its Reports -Would your Planning Department provide these" <br />The need for better ;mall particle modeling <br />City of Santa Ana <br />AirVisuaI Outdoor Monitor <br />TMe ulllepme ou[doar alr walky mwiuor. PmYRW Vw with hypardml. reel-tlme ak <br />qua Nysurrauldingyaurhame, shod, arbisi ass. [Urat(Drmaasuring air <br />PAUtim eapoeana i ram tropic, Irrdu aery, awlckAwd b urrkt o or wil4ree. Uew real- <br />time and liv&ie alr"IhyvialheTree motile app, Share youree Nr OmWill <br />millioraofuserswdhIha*Air Airwr alapp. <br />FREE Fast OeMmry Il arria Daly Shipping <br />S299-99 <br />5tarlinR at &NVmo ar O-A APR with a%rm.: heck your purchasing power <br />Page 4 <br />15-2 <br />cont- <br />August 2025 <br />15 <br />