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RECRUITMENTS=x r <br />As part of a contract with the city of Santa Ana, the UCI Program in Public Health will design and <br />implement COVID-19 serosurveillance of 8,000 Santa Ana residents over the age of five from <br />October - December 2020. UCI will employ randomized cluster sampling by census tract, overseen <br />by Dr. Boden-Albala, Dr. Ryan, and Dr. Wing. Participants will be given an antibody test following <br />completion of a short survey. UCI will contract local community organizations to consult on <br />development of the survey and sampling strategy and to assist with systematic recruitment of <br />participants in English, Spanish, and/or Vietnamese, including a targeted media and information <br />campaign to encourage community engagement. UCI will provide incentives for participation. <br />Recruitment will begin following approval of the protocol by the UCI IRB. Dr. Runnerstrom will <br />oversee operations of UCI's assistance with Santa Ana's online chat line and phone line, which will <br />be available daily to respond to residents' questions about the project. <br />Dr. Parker will oversee testing procedures, with logistical managerial support from Dr. Albala and <br />Ms. Drum. UCI will contract Maypl to schedule and conduct in -home appointments for COVID <br />IgG/IgM rapid serum tests that will require a finger stick capillary tube procedure. The Feigner lab <br />will quantify antibody titer to COVID-19 using its UCI microarray platform. <br />MODELING <br />Dr. Ryan, Dr. Wing, and Dr. Parker will oversee data analysis. UCI will use serosurveillance data to <br />develop models that will forecast the trajectory of COVID-19 in Santa Ana. <br />Project Timeline <br />Date <br />Activity <br />9/15/20- <br />Develop sampling and recruitment strategy <br />10 1 20 <br />10/1/20- <br />Recruit participants and conduct in -home testing on 8,000 Santa Ana residents; <br />12 30 20 <br />provide hel line access for participant questions <br />1/1/21- <br />Analyze results; develop predictive models; issue report to city of Santa Ana; <br />2/1/21 <br />submit results to high -impact peer reviewed journal (this will be a part of a final <br />report that is due as part of the close-out activities <br />21 <br />